Unlocking the Healing Power of Extracellular Matrix
Extracellular Matrix (ECM) signaling molecules mitigate inflammation and restore function to damaged tissue, muscle, and nerve cells.
ECM Therapeutics
ECM Therapeutics, Inc. is a regenerative medicine company that develops and manufactures therapeutic products derived from a naturally occurring material called extracellular matrix (ECM).
Extracellular matrix is a naturally occurring reservoir of potent signaling molecules within all tissues and has the ability to influence cell behavior, control inflammation, and promote the restoration of functional tissue following injury.
Regenerative Medicine Pioneer
Dr. Stephen Badylak's laboratory is a world-renowned and highly interdisciplinary environment focused on developing regenerative medicine strategies that address significant clinical needs.
Extensive bench-top laboratory work, preclinical animal studies, human clinical experience with alternative forms of ECM-based materials, scientific publications, and an extensive patent portfolio have strategically positioned ECM Therapeutics to develop products in a number of different clinical markets including the gastrointestinal, musculoskeletal, optic and central nervous system.
Publications
This review highlights the fundamental characteristics of EVs, the current pre-clinical and clinical applications of EVs in TERM, and the future of EV-based strategies in TERM
Read MoreThe native mammalian ECM constitutes an ideal microenvironmental niche for functional tissue reconstruction. The ECM contains intrinsic biochemical and mechanical cues that regulate cell phenotype and function in development, in homeostasis and in response to injury.
Read MoreThe identification of MBVs embedded within the ECM of biologic scaffolds provides mechanistic insights not only into the inductive properties of ECM bioscaffolds but also into the regulation of tissue homeostasis.
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