December 22, 2020 Journal of Immunology and Regenerative Medicine

The effect of normal, metaplastic, and neoplastic esophageal extracellular matrix upon macrophage activation

Lindsey T.Saldin, Molly Klimaka, Ryan C.Hill, Madeline C. Cramer, Luai Huleihel, Xue Li, Maria Quidgley-Martina, David Cardenas, Timothy J. Keane, Ricardo London, George Hussey, Lori Kelly, Juliann E. Kosovec, Emily J. Lloyd, Ashten N. Omstead, Li Zhang, Alejandro Nieponice, Blair Jobe, Stephen F. Badylak
December 8, 2020 ScienceDirect Elsevier

ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke

Harmanvir Ghuman, Rita Matta, Alexandra Tompkins, Franziska Nitzsche, Stephen F. Badylak, Anjelica L. Gonzalez, Michel Modo
October 19, 2020 Tissue Engineering

Matrix-Bound Nanovesicles: The Effects of Isolation Method upon Yield, Purity, and Function

Lina M. Quijano, Juan D. Naranjo, Salma O. El-Mossier, Neill J. Turner, Catalina Pineda Molina, Joseph Bartolacci, Li Zhang, Lisa White, Hui Li, and Stephen F. Badylak
July 9, 2020 The Journal of Clinical Investigation

Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection

Teng fang Li, Zhong qiang Zhang, Joe G. Bartolacci, Gaelen K. Dwyer, Quan Liu, Lisa R. Mathews, Murugesan Velayutham, Anna S. Roessing, Yoojin C. Lee, Helong Dai, Sruti Shiva, Martin H. Oberbarnscheidt, Jenna L. Dziki, Steven J. Mullet, Stacy G. Wendell, James D. Wilkinson, Steven A. Webber, Michelle Wood-Trageser, Simon C. Watkins, Anthony J. Demetris, George S. Hussey, Stephen F. Badylak, and Hēth R. Turnquist
July 1, 2020 Science Advances

Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus

Juan Diego Naranjo, Lindsey T. Saldin, Eric Sobieski, Lina M. Quijano, Ryan C. Hill, Patrick G. Chan, Crisanto Torres, Jenna L. Dziki, Madeline C. Cramer, Yoojin C. Lee, Rohit Das, Anant K. Bajwa, Rania Nossair, Molly Klimak, Lucile Marchal, Shil Patel, Sachin S. Velankar, Kirk C. Hansen, Kevin McGrath, Stephen F. Badylak
March 20, 2020 Science Advances

Lipidomics and RNA sequencing reveal a novel subpopulation of nanovesicle within extracellular matrix biomaterials

George S. Hussey, Catalina Pineda Molina, Madeline C. Cramer, Yulia Y. Tyurina, Vladimir A. Tyurin, Yoojin C. Lee, Salma O. El-Mossier, Mark H. Murdock, Peter S. Timashev, Valerian E. Kagan, Stephen F. Badylak
March 5, 2019 Nature Scientific Reports

Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function

Yolandi van der Merwe, Anne E. Faust, Ecem T. Sakalli, Caroline C. Westrick, George Hussey, Ian P. Conner, Valeria L. N. Fu, Stephen F. Badylak & Michael B. Steketee
February 1, 2019 Journal of Immunology and Regenerative Medicine

Matrix bound nanovesicle-associated IL-33 activates a pro-remodeling macrophage phenotype via a non-canonical, ST2-independent pathway

George S. Hussey, Jenna L. Dziki, Yoojin C. Lee, Joseph G. Bartolacci, Marissa Behun, Hēth R. Turnquist, Stephen F. Badylak
December 26, 2018 Journal of Immunology and Regenerative Medicine

Comparison of the host macrophage response to synthetic and biologic surgical meshes used for ventral hernia repair

Catalina Pineda Molina, Ross Giglio, Riddhi M. Gandhi, Brian M. Sicari, Ricardo Londono, George S. Hussey, Joseph G. Bartolacci, Lina M. Quijano Luque, Madeline C. Cramer, Jenna L. Dziki, Peter M. Crapo, Stephen F. Badylak
October 15, 2018 Acta Biomaterialia

Biodegradation of ECM hydrogel promotes endogenous brain tissue restoration in a rat model of stroke

Harmanvir Ghuman, Carrinton Mauney, Julia Donnelly, Andre R. Massensini, Stephen F. Badylak, Michel Modo
October 12, 2018 Tissue Engineering

Human testis extracellular matrix enhances human spermatogonial stem cell survival in vitro

Mr. Mark H. Murdock, Miss Sherin David, Miss Ilea T. Swinehart, Mrs. Janet E. Reing, Miss Kien Tran, Dr. Kathrin Gassei, Dr. Kyle E. Orwig, Dr. Stephen F Badylak
September 28, 2018 The Journal of Thoracic and Cardiovascular Surgery

Cytocompatibility and mechanical properties of surgical sealants for cardiovascular applications

Mark H. Murdock, BSc, Jordan T. Chang, BA, Samuel K. Luketich, MS, Drake Pedersen, BSc, George S. Hussey, PhD, Antonio D’Amore, PhD, and Stephen F. Badylak, MD, PhD, DVM
September 27, 2018 Tissue Engineering

Extracellular matrix degradation products downregulate neoplastic esophageal cell phenotype

Miss Lindsey Tamiko Saldin, Mr. Shil Patel, Dr. Li Zhang, Dr. Luai Huleihel, Dr. George S. Hussey, Mr. David Gabriele Nascari, Dr. Lina Maria Quijano, Dr. Xue Li, Miss Divya Raghu, Miss Anant Kaur Bajwa, Mr. Nicholas G. Smith, Mr. Christopher Chi-Heng Chung, Miss Ashten N. Omstead, Miss Juliann E. Kosovec, Dr. Blair A. Jobe, Dr. Neill J Turner, Dr. Ali H. Zaidi, and Dr. Stephen F Badylak
May 29, 2018 Nature Reviews Materials

Extracellular matrix-based materials for regenerative medicine

George S. Hussey, Jenna L. Dziki & Stephen F. Badylak
September 10, 2016 Journal of Crohn's and Colitis

Restoring Mucosal Barrier Function and Modifying Macrophage Phenotype with an Extracellular Matrix Hydrogel: Potential Therapy for Ulcerative Colitis

Timothy J. Keane, Jenna Dziki, Eric Sobieski, Adam Smoulder, Arthur Castleton, Neill Turner, Lisa J. White, Stephen F. Badylak
July 21, 2016 npj Regenerative Medicine

An acellular biologic scaffold treatment for volumetric muscleloss: results of a 13-patient cohort study

Jenna Dziki, Stephen Badylak, Mohammad Yabroudi, Brian Sicari, Fabrisia Ambrosio, Kristen Stearns, Neill Turner, Aaron Wyse, Michael L Boninger, Elke HP Brown and J Peter Rubin
June 10, 2016 Science Advances

Matrix-bound nanovesicles within ECM bioscaffolds

Luai Huleihel, George S. Hussey, Juan Diego Naranjo, Li Zhang, Jenna L. Dziki, Neill J. Turner, Donna B. Stolz, Stephen F. Badylak
August 12, 2015 Tissue Engineering

Tissue-Specific Effects of Esophageal Extracellular Matrix

Timothy J. Keane, Aaron DeWard, Ricardo Londono, Lindsey T. Saldin, Arthur A. Castleton, Lisa Carey, Alejandro Nieponice, Eric Lagasse, and Stephen F. Badylak
March 28, 2011 Tissue Engineering

Esophageal Preservation in Five Male Patients After Endoscopic Inner-Layer Circumferential Resection in the Setting of Superficial Cancer: A Regenerative Medicine Approach with a Biologic Scaffold

Stephen F. Badylak, Toshitaka Hoppo, Alejandro Nieponice, Thomas W. Gilbert, Jon M. Davison, and Blair A. Jobe